Which medication can be safely crushed before administration?

Crushing medications before administration is a significant consideration in medication management, especially concerning how the medication is designed to be delivered and absorbed in the body. When looking at the medications listed, Bactrim D.S. is the one that can be safely crushed prior to administration.

Bactrim D.S. is an antibiotic that consists of sulfamethoxazole and trimethoprim. Unlike the other options, it is not specifically formulated as a delayed-release or enteric-coated medication, which would require a certain integrity to ensure it is absorbed properly in the digestive system. Crushing Bactrim D.S. does not compromise its effectiveness or alter how the body absorbs the medication.

In contrast, ASA Enseals are enteric-coated, meaning that the coating is designed to protect the stomach lining from the medicine and also ensures that it does not dissolve until it reaches the intestines. Crushing this medication would negate that safety mechanism, potentially leading to gastric irritation or irregular absorption.

Hydergine, which is intended for sublingual use, is designed to dissolve under the tongue for rapid absorption. Crushing it would alter its delivery and effectiveness.

Feosol Spansules are sustained-release capsules that are formulated to release their contents gradually over time. Crushing these